# High-flow Oxygen for Vaso-occlusive Pain Crisis

> **NCT03976180** · NA · RECRUITING · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 350 (estimated)

## Conditions studied

- Sickle Cell Disease

## Interventions

- **DEVICE:** Stadard low-flow oxygen
- **DEVICE:** HFNO with low FiO2 (21%-30%)
- **DEVICE:** HFNO with intermediate FiO2 (50%)
- **DEVICE:** HFNO with high FiO2 (100%)

## Key facts

- **NCT ID:** NCT03976180
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2020-04-27
- **Primary completion:** 2025-11-27
- **Final completion:** 2025-11-27
- **Target enrollment:** 350 (ESTIMATED)
- **Last updated:** 2025-07-28

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03976180

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03976180, "High-flow Oxygen for Vaso-occlusive Pain Crisis". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT03976180. Licensed CC0.

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