# Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related Disorders

> **NCT03981276** · — · RECRUITING · sponsor: **Dr. Rebecca Schule** · enrollment: 2000 (estimated)

## Conditions studied

- Hereditary Spastic Paraplegia

## Interventions

- **OTHER:** Clinical rating scale to measure disease severity and progression
- **DIAGNOSTIC_TEST:** Next-Gen Sequencing (NGS)

## Key facts

- **NCT ID:** NCT03981276
- **Lead sponsor:** Dr. Rebecca Schule
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2019-10-14
- **Primary completion:** 2039-08
- **Final completion:** 2041-08
- **Target enrollment:** 2000 (ESTIMATED)
- **Last updated:** 2021-05-19

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03981276

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03981276, "Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related Disorders". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT03981276. Licensed CC0.

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