# Comparison of Topical Silymarin With Hydroquinone in the Treatment of Melasma

> **NCT03982849** · PHASE2 · COMPLETED · sponsor: **Islamabad Medical and Dental College** · enrollment: 92 (actual)

## Conditions studied

- Melasma

## Interventions

- **DRUG:** Hydroquinone 4% Cream
- **DRUG:** silymarin 0.7% cream

## Key facts

- **NCT ID:** NCT03982849
- **Lead sponsor:** Islamabad Medical and Dental College
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-07-15
- **Primary completion:** 2019-12-31
- **Final completion:** 2020-01-15
- **Target enrollment:** 92 (ACTUAL)
- **Last updated:** 2020-02-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03982849

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03982849, "Comparison of Topical Silymarin With Hydroquinone in the Treatment of Melasma". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT03982849. Licensed CC0.

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