# Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial

> **NCT03997643** · PHASE2 · RECRUITING · sponsor: **London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's** · enrollment: 90 (estimated)

## Conditions studied

- Head and Neck Cancer

## Interventions

- **RADIATION:** Radiotherapy to all dissected areas
- **RADIATION:** Omit radiation to pN0 neck

## Key facts

- **NCT ID:** NCT03997643
- **Lead sponsor:** London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2019-09-06
- **Primary completion:** 2026-09
- **Final completion:** 2026-09
- **Target enrollment:** 90 (ESTIMATED)
- **Last updated:** 2023-08-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT03997643

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT03997643, "Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT03997643. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*