# Effects of 5HTP and LDOPA on CNS Excitability After SCI

> **NCT04000919** · PHASE2,PHASE3 · SUSPENDED · sponsor: **Jessica M D'Amico** · enrollment: 30 (estimated)

## Conditions studied

- Spinal Cord Injuries

## Interventions

- **DRUG:** 5HTP
- **DRUG:** L-DOPA
- **DRUG:** Placebo oral tablet
- **DRUG:** Carbidopa

## Key facts

- **NCT ID:** NCT04000919
- **Lead sponsor:** Jessica M D'Amico
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** SUSPENDED
- **Start date:** 2019-06-19
- **Primary completion:** 2023-06-30
- **Final completion:** 2023-12-30
- **Target enrollment:** 30 (ESTIMATED)
- **Why stopped:** PI left UofL and intends to reopen study at University of Alberta
- **Last updated:** 2022-10-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04000919

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04000919, "Effects of 5HTP and LDOPA on CNS Excitability After SCI". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT04000919. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*