# SMART Use of Medication for the Treatment of Adolescent Severe Obesity

> **NCT04007393** · PHASE2 · COMPLETED · sponsor: **University of Minnesota** · enrollment: 150 (actual)

## Conditions studied

- Adolescent Obesity

## Interventions

- **BEHAVIORAL:** Lifestyle Modification Therapy (LSMT)
- **DRUG:** Phentermine Pill
- **DRUG:** Topiramate Pill
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04007393
- **Lead sponsor:** University of Minnesota
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-11-21
- **Primary completion:** 2025-03-11
- **Final completion:** 2025-03-11
- **Target enrollment:** 150 (ACTUAL)
- **Last updated:** 2026-05-05

## Collaborators

- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04007393

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04007393, "SMART Use of Medication for the Treatment of Adolescent Severe Obesity". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT04007393. Licensed CC0.

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