# Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels

> **NCT04008368** · PHASE1,PHASE2 · RECRUITING · sponsor: **National Heart, Lung, and Blood Institute (NHLBI)** · enrollment: 32 (estimated)

## Conditions studied

- Myeloid Chimerism

## Interventions

- **DEVICE:** CliniMACS CD34 Reagent

## Key facts

- **NCT ID:** NCT04008368
- **Lead sponsor:** National Heart, Lung, and Blood Institute (NHLBI)
- **Sponsor class:** NIH
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2019-10-24
- **Primary completion:** 2030-01-30
- **Final completion:** 2037-12-01
- **Target enrollment:** 32 (ESTIMATED)
- **Last updated:** 2026-02-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04008368

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04008368, "Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04008368. Licensed CC0.

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