# Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

> **NCT04031677** · PHASE3 · RECRUITING · sponsor: **European Organisation for Research and Treatment of Cancer - EORTC** · enrollment: 250 (estimated)

## Conditions studied

- Retroperitoneal Sarcoma
- Liposarcoma
- Leiomyosarcoma

## Interventions

- **PROCEDURE:** Surgery
- **DRUG:** Preoperative chemotherapy

## Key facts

- **NCT ID:** NCT04031677
- **Lead sponsor:** European Organisation for Research and Treatment of Cancer - EORTC
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-01-20
- **Primary completion:** 2027-04-21
- **Final completion:** 2028-04-21
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2026-03-31

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04031677

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04031677, "Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04031677. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
