# Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension

> **NCT04039464** · PHASE3 · COMPLETED · sponsor: **Johns Hopkins University** · enrollment: 28 (actual)

## Conditions studied

- Pediatric Pulmonary Hypertension

## Interventions

- **DRUG:** Mono-Therapy with Sildenafil
- **DRUG:** Duo-Therapy with Sildenafil + Bosentan

## Key facts

- **NCT ID:** NCT04039464
- **Lead sponsor:** Johns Hopkins University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-08-01
- **Primary completion:** 2025-12-31
- **Final completion:** 2025-12-31
- **Target enrollment:** 28 (ACTUAL)
- **Last updated:** 2026-02-18

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04039464

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04039464, "Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04039464. Licensed CC0.

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