ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)

NCT04049513 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

30

Enrollment

OTHER

Sponsor class

Conditions

Lymphomas Non-Hodgkin's B-Cell
Diffuse Large B-cell Lymphoma (DLBCL)
Primary Mediastinal B-cell Lymphoma (PMBCL)
Transformed Follicular Lymphoma (TFL)
Follicular Lymphoma (FL)
Mantle Cell Lymphoma (MCL)

Interventions

BIOLOGICAL: WZTL002-1 (1928T2z CAR-T cells)
DRUG: Cyclophosphamide and Fludarabine lymphodepleting chemotherapy

Sponsor

Malaghan Institute of Medical Research

Collaborators

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