# Sorafenib PK in Patients With Advanced HCC and Child-Pugh B

> **NCT04051853** · PHASE2 · TERMINATED · sponsor: **Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)** · enrollment: 5 (actual)

## Conditions studied

- BCLC Stage C HCC
- CP-B Liver Cirrhosis

## Interventions

- **DRUG:** Sorafenib
- **OTHER:** Midazolam clearance test
- **OTHER:** CYP cocktail clearance test

## Key facts

- **NCT ID:** NCT04051853
- **Lead sponsor:** Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2014-05
- **Primary completion:** 2017-03
- **Final completion:** 2017-03
- **Target enrollment:** 5 (ACTUAL)
- **Why stopped:** Slow accrual.
- **Last updated:** 2019-08-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04051853

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04051853, "Sorafenib PK in Patients With Advanced HCC and Child-Pugh B". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT04051853. Licensed CC0.

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