# RANKL Inhibition and Mammographic Breast Density

> **NCT04067726** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Washington University School of Medicine** · enrollment: 210 (actual)

## Conditions studied

- Dense Breasts

## Interventions

- **DRUG:** Denosumab
- **DRUG:** Placebo
- **DRUG:** Calcium
- **DRUG:** Vitamin D3
- **PROCEDURE:** Core needle biopsy
- **PROCEDURE:** Blood draw

## Key facts

- **NCT ID:** NCT04067726
- **Lead sponsor:** Washington University School of Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2019-08-27
- **Primary completion:** 2025-09-17
- **Final completion:** 2026-08-31
- **Target enrollment:** 210 (ACTUAL)
- **Last updated:** 2026-03-31

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04067726

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04067726, "RANKL Inhibition and Mammographic Breast Density". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04067726. Licensed CC0.

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