# SMART Trial for Buprenorphine-Naloxone Medication Assisted Treatment Adherence

> **NCT04080180** · NA · COMPLETED · sponsor: **Karen Derefinko, PhD** · enrollment: 332 (actual)

## Conditions studied

- Opioid-use Disorder

## Interventions

- **BEHAVIORAL:** Contingency Management
- **BEHAVIORAL:** Brief Motivational Interviewing + Substance Free Activities + Mindfulness

## Key facts

- **NCT ID:** NCT04080180
- **Lead sponsor:** Karen Derefinko, PhD
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-02-01
- **Primary completion:** 2025-02-01
- **Final completion:** 2025-02-01
- **Target enrollment:** 332 (ACTUAL)
- **Last updated:** 2025-02-25

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04080180

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04080180, "SMART Trial for Buprenorphine-Naloxone Medication Assisted Treatment Adherence". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT04080180. Licensed CC0.

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