# Induction of Gut Permeability by an Oral Vaccine

> **NCT04083950** · EARLY_PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **USDA, Western Human Nutrition Research Center** · enrollment: 10 (actual)

## Conditions studied

- Intestinal Permeability
- Inflammation
- Vaccine
- Typhoid Fever

## Interventions

- **BIOLOGICAL:** Vivotif Typhoid Oral Vaccine
- **DRUG:** Aspirin (Positive Control)

## Key facts

- **NCT ID:** NCT04083950
- **Lead sponsor:** USDA, Western Human Nutrition Research Center
- **Sponsor class:** FED
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2019-12-04
- **Primary completion:** 2022-01-31
- **Final completion:** 2026-09-30
- **Target enrollment:** 10 (ACTUAL)
- **Last updated:** 2025-11-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04083950

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04083950, "Induction of Gut Permeability by an Oral Vaccine". Retrieved via AI Analytics 2026-07-19 from https://api.ai-analytics.org/clinical/NCT04083950. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*