# Perioperative Lidocaine and Ketamine in Abdominal Surgery

> **NCT04084548** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **The Cleveland Clinic** · enrollment: 420 (estimated)

## Conditions studied

- Postoperative Pain

## Interventions

- **DRUG:** Lidocaine and ketamine
- **DRUG:** Lidocaine
- **DRUG:** Ketamine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04084548
- **Lead sponsor:** The Cleveland Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2019-10-15
- **Primary completion:** 2025-12
- **Final completion:** 2025-12
- **Target enrollment:** 420 (ESTIMATED)
- **Last updated:** 2025-05-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04084548

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04084548, "Perioperative Lidocaine and Ketamine in Abdominal Surgery". Retrieved via AI Analytics 2026-07-02 from https://api.ai-analytics.org/clinical/NCT04084548. Licensed CC0.

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