# Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapy

> **NCT04090736** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **PETHEMA Foundation** · enrollment: 302 (actual)

## Conditions studied

- Leukemia, Myeloid, Acute

## Interventions

- **DRUG:** Pevonedistat
- **DRUG:** Azacitidine

## Key facts

- **NCT ID:** NCT04090736
- **Lead sponsor:** PETHEMA Foundation
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2019-09-24
- **Primary completion:** 2023-06-30
- **Final completion:** 2025-06-30
- **Target enrollment:** 302 (ACTUAL)
- **Last updated:** 2025-03-17

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04090736

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04090736, "Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapy". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04090736. Licensed CC0.

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