# Sirolimus for Cowden Syndrome With Colon Polyposis

> **NCT04094675** · PHASE2 · COMPLETED · sponsor: **Ohio State University** · enrollment: 5 (actual)

## Conditions studied

- PTEN Gene Mutation
- PTEN Hamartoma Tumor Syndrome
- PTEN Hamartoma Syndrome
- Cowden Syndrome
- Bannayan Syndrome
- Bannayan Zonana Syndrome
- Polyposis

## Interventions

- **DRUG:** Sirolimus

## Key facts

- **NCT ID:** NCT04094675
- **Lead sponsor:** Ohio State University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-09-16
- **Primary completion:** 2025-02-01
- **Final completion:** 2025-06-05
- **Target enrollment:** 5 (ACTUAL)
- **Last updated:** 2025-06-10

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04094675

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04094675, "Sirolimus for Cowden Syndrome With Colon Polyposis". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT04094675. Licensed CC0.

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