# Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia

> **NCT04100057** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Stanford University** · enrollment: 150 (estimated)

## Conditions studied

- Alzheimer Disease
- Mild Cognitive Impairment
- Neuropsychiatric Symptoms
- Sleep Disturbance

## Interventions

- **BEHAVIORAL:** Cognitive Behavioral Therapy for Insomnia (CBT-I)
- **BEHAVIORAL:** Desensitization Therapy for insomnia (DT-I)

## Key facts

- **NCT ID:** NCT04100057
- **Lead sponsor:** Stanford University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2021-08-31
- **Primary completion:** 2026-04-30
- **Final completion:** 2026-11-30
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2026-04-20

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04100057

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04100057, "Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT04100057. Licensed CC0.

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