# Inherited Genetic Susceptibility in Langerhans Cell Histiocytosis (LCH)

> **NCT04100408** · — · ACTIVE_NOT_RECRUITING · sponsor: **Children's Oncology Group** · enrollment: 647 (estimated)

## Conditions studied

- Histiocytosis, Langerhans-Cell

## Interventions

- **OTHER:** Biospecimen Collection
- **OTHER:** Laboratory Biomarker Analysis
- **OTHER:** Questionnaire Administration

## Key facts

- **NCT ID:** NCT04100408
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-06-01
- **Primary completion:** 2026-09-30
- **Final completion:** 2026-09-30
- **Target enrollment:** 647 (ESTIMATED)
- **Last updated:** 2026-01-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04100408

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04100408, "Inherited Genetic Susceptibility in Langerhans Cell Histiocytosis (LCH)". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04100408. Licensed CC0.

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