# Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

> **NCT04102371** · PHASE3 · COMPLETED · sponsor: **Children's Hospital of Philadelphia** · enrollment: 9041 (actual)

## Conditions studied

- Shock
- Septic

## Interventions

- **DRUG:** Lactated Ringer
- **DRUG:** Normal Saline
- **DRUG:** Plasma-lyte

## Key facts

- **NCT ID:** NCT04102371
- **Lead sponsor:** Children's Hospital of Philadelphia
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-08-25
- **Primary completion:** 2025-12-01
- **Final completion:** 2026-01-31
- **Target enrollment:** 9041 (ACTUAL)
- **Last updated:** 2026-03-05

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04102371

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04102371, "Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT04102371. Licensed CC0.

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