# How TKA Implants Affect Muscle Quality and Activity During Daily Living and Immunological Response

> **NCT04105179** · NA · UNKNOWN · sponsor: **Ottawa Hospital Research Institute** · enrollment: 75 (estimated)

## Conditions studied

- Osteoarthritis, Knee
- Inflammation Knees

## Interventions

- **DEVICE:** Zimmer NexGen LPS-Flex
- **DEVICE:** Smith & Nephew Journey II

## Key facts

- **NCT ID:** NCT04105179
- **Lead sponsor:** Ottawa Hospital Research Institute
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2019-04-29
- **Primary completion:** 2023-12
- **Final completion:** 2023-12
- **Target enrollment:** 75 (ESTIMATED)
- **Last updated:** 2022-08-08

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04105179

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04105179, "How TKA Implants Affect Muscle Quality and Activity During Daily Living and Immunological Response". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT04105179. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*