# Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease

> **NCT04114981** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **Alliance for Clinical Trials in Oncology** · enrollment: 242 (actual)

## Conditions studied

- Metastatic Malignant Neoplasm in the Brain

## Interventions

- **RADIATION:** Single Fraction Stereotactic Radiosurgery
- **RADIATION:** Fractionated Stereotactic Radiosurgery
- **PROCEDURE:** Quality-of-Life Assessment
- **OTHER:** Questionnaire Administration

## Key facts

- **NCT ID:** NCT04114981
- **Lead sponsor:** Alliance for Clinical Trials in Oncology
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2019-11-19
- **Primary completion:** 2026-09-01
- **Final completion:** 2028-09
- **Target enrollment:** 242 (ACTUAL)
- **Last updated:** 2026-04-21

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04114981

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04114981, "Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT04114981. Licensed CC0.

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