# Antidepressant Trial With P2X7 Antagonist JNJ-54175446

> **NCT04116606** · PHASE2 · UNKNOWN · sponsor: **CCTU-Core** · enrollment: 142 (estimated)

## Conditions studied

- Depressive Disorder, Major
- Inflammation

## Interventions

- **DRUG:** Active JNJ-54175446
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT04116606
- **Lead sponsor:** CCTU-Core
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2019-09-12
- **Primary completion:** 2023-12-31
- **Final completion:** 2024-06-30
- **Target enrollment:** 142 (ESTIMATED)
- **Last updated:** 2022-06-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04116606

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04116606, "Antidepressant Trial With P2X7 Antagonist JNJ-54175446". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04116606. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
