Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer
ACTIVE_NOT_RECRUITING
Status
Conditions
- BRAF V600E Negative
- KRAS Gene Mutation Negative
- Locally Advanced Unresectable Colorectal Adenocarcinoma
- Metastatic Colorectal Adenocarcinoma
- NRAS Gene Mutation Negative
- Stage III Colorectal Cancer AJCC v8
- Stage IIIA Colorectal Cancer AJCC v8
- Stage IIIB Colorectal Cancer AJCC v8
- Stage IIIC Colorectal Cancer AJCC v8
- Stage IV Colorectal Cancer AJCC v8
- Stage IVA Colorectal Cancer AJCC v8
- Stage IVB Colorectal Cancer AJCC v8
- Stage IVC Colorectal Cancer AJCC v8
Interventions
- BIOLOGICAL: Cetuximab
- DRUG: Irinotecan
- BIOLOGICAL: Panitumumab
- DRUG: Regorafenib
Sponsor
Academic and Community Cancer Research United
Collaborators