# Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

> **NCT04124029** · — · RECRUITING · sponsor: **VA Office of Research and Development** · enrollment: 800 (estimated)

## Conditions studied

- Mild Traumatic Brain Injury
- Moderate Traumatic Brain Injury
- Mild Cognitive Impairment

## Interventions

- **DEVICE:** No Intervention is used for this study but all subjects will be asked to complete EEG testing and an MRI scan.
- **PROCEDURE:** No intervention is used for this study but all subjects will be asked to complete a venous blood draw procedure and a lumbar puncture procedure.

## Key facts

- **NCT ID:** NCT04124029
- **Lead sponsor:** VA Office of Research and Development
- **Sponsor class:** FED
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2021-07-01
- **Primary completion:** 2026-06-30
- **Final completion:** 2026-06-30
- **Target enrollment:** 800 (ESTIMATED)
- **Last updated:** 2025-09-26

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04124029

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04124029, "Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT04124029. Licensed CC0.

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