# Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs

> **NCT04140266** · PHASE3 · COMPLETED · sponsor: **National Institute of Allergy and Infectious Diseases (NIAID)** · enrollment: 394 (actual)

## Conditions studied

- HIV Infections

## Interventions

- **DRUG:** Dapivirine (DPV) Vaginal Ring (VR)-004
- **DRUG:** Truvada Tablet

## Key facts

- **NCT ID:** NCT04140266
- **Lead sponsor:** National Institute of Allergy and Infectious Diseases (NIAID)
- **Sponsor class:** NIH
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-09-24
- **Primary completion:** 2021-11-04
- **Final completion:** 2021-11-04
- **Target enrollment:** 394 (ACTUAL)
- **Last updated:** 2023-08-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04140266

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04140266, "Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04140266. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*