# SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

> **NCT04150042** · PHASE1 · RECRUITING · sponsor: **General Oncology, Inc.** · enrollment: 24 (estimated)

## Conditions studied

- Pancreatic Adenocarcinoma Metastatic
- BRCA1 Mutation
- BRCA2 Mutation
- Pancreatic Acinar Cell Carcinoma
- Pancreatic Ductal Adenocarcinoma
- Pancreatic Cancer
- Metastatic Pancreatic Cancer
- Metastatic Pancreatic Ductal Adenocarcinoma
- Breast Cancer Metastatic
- Breast Cancer Stage IV
- Pancreatic Cancer Stage IV
- HER2-negative Breast Cancer
- HER2 Negative Breast Carcinoma
- Adenocarcinoma of the Breast
- PALB2 Gene Mutation
- Pancreas Cancer, Metastatic
- Pancreas Cancer, Recurrent
- Pancreas Cancer
- Stage IV Pancreatic Cancer
- Stage 4 Pancreatic Cancer

## Interventions

- **DRUG:** Melphalan
- **DRUG:** BCNU
- **DRUG:** Vitamin B12B
- **DRUG:** Vitamin C
- **DEVICE:** Autologous Hematopoietic Stem Cells

## Key facts

- **NCT ID:** NCT04150042
- **Lead sponsor:** General Oncology, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-01-13
- **Primary completion:** 2028-12
- **Final completion:** 2028-12
- **Target enrollment:** 24 (ESTIMATED)
- **Last updated:** 2026-01-29

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04150042

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04150042, "SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells". Retrieved via AI Analytics 2026-06-29 from https://api.ai-analytics.org/clinical/NCT04150042. Licensed CC0.

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