# Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty

> **NCT04166539** · — · COMPLETED · sponsor: **Mayo Clinic** · enrollment: 115 (actual)

## Conditions studied

- Metallosis
- Pain
- Total Hip Replacement
- Total Knee Replacement

## Interventions

- **BEHAVIORAL:** Questionnaires
- **BEHAVIORAL:** Interviews
- **OTHER:** Blood draw
- **RADIATION:** Magnetic Resonance Imaging
- **DIAGNOSTIC_TEST:** Echocardiogram

## Key facts

- **NCT ID:** NCT04166539
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2019-10-01
- **Primary completion:** 2021-09-27
- **Final completion:** 2021-09-27
- **Target enrollment:** 115 (ACTUAL)
- **Last updated:** 2021-12-08

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04166539

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04166539, "Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty". Retrieved via AI Analytics 2026-09-04 from https://api.ai-analytics.org/clinical/NCT04166539. Licensed CC0.

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