# Varenicline and Bupropion for Alcohol Use Disorder

> **NCT04167306** · PHASE2 · COMPLETED · sponsor: **Vastra Gotaland Region** · enrollment: 388 (actual)

## Conditions studied

- Alcohol Use Disorder
- Alcoholism
- Alcohol Dependence

## Interventions

- **DRUG:** Varenicline Tartrate 1 mg b.i.d
- **DRUG:** Bupropion Hydrochloride 150 mg b.i.d
- **OTHER:** Placebo for varenicline
- **OTHER:** Placebo for bupropion

## Key facts

- **NCT ID:** NCT04167306
- **Lead sponsor:** Vastra Gotaland Region
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-03-04
- **Primary completion:** 2022-12-15
- **Final completion:** 2022-12-15
- **Target enrollment:** 388 (ACTUAL)
- **Last updated:** 2024-06-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04167306

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04167306, "Varenicline and Bupropion for Alcohol Use Disorder". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04167306. Licensed CC0.

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