# Using rTMS to Explore Neural Mechanisms of Stress-Induced Opioid Use

> **NCT04181515** · PHASE2 · WITHDRAWN · sponsor: **Wayne State University**

## Conditions studied

- Stress
- Opioid-use Disorder

## Interventions

- **DRUG:** Placebo oral tablet
- **DRUG:** Yohimbine + Hydrocortisone
- **DEVICE:** sham rTMS
- **DEVICE:** active rTMS

## Key facts

- **NCT ID:** NCT04181515
- **Lead sponsor:** Wayne State University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2023-04-10
- **Primary completion:** 2023-04-10
- **Final completion:** 2023-04-10
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** Lack of funding
- **Last updated:** 2023-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04181515

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04181515, "Using rTMS to Explore Neural Mechanisms of Stress-Induced Opioid Use". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04181515. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*