# Age Comparisons of Exercising Muscle O2 Supply in Healthy Adults: Effects of Esmolol Infusion

> **NCT04181606** · EARLY_PHASE1 · COMPLETED · sponsor: **David N. Proctor, PhD** · enrollment: 30 (actual)

## Conditions studied

- Aging

## Interventions

- **DRUG:** Esmolol infusion
- **DRUG:** Saline infusion
- **OTHER:** Pre exercise baseline
- **OTHER:** Isometric handgrip exercise
- **OTHER:** Semi-recumbent cycling

## Key facts

- **NCT ID:** NCT04181606
- **Lead sponsor:** David N. Proctor, PhD
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-02-02
- **Primary completion:** 2023-04-25
- **Final completion:** 2023-04-25
- **Target enrollment:** 30 (ACTUAL)
- **Last updated:** 2025-05-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04181606

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04181606, "Age Comparisons of Exercising Muscle O2 Supply in Healthy Adults: Effects of Esmolol Infusion". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04181606. Licensed CC0.

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