# Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes

> **NCT04183218** · — · COMPLETED · sponsor: **Mayo Clinic** · enrollment: 24 (actual)

## Conditions studied

- Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8
- Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8
- Clinical Stage I Esophageal Adenocarcinoma AJCC v8
- Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8
- Clinical Stage II Esophageal Adenocarcinoma AJCC v8
- Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8
- Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8
- Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8
- Clinical Stage III Esophageal Adenocarcinoma AJCC v8
- Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8
- Localized Esophageal Carcinoma
- Localized Lung Carcinoma
- Pathologic Stage 0 Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8
- Pathologic Stage I Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage I Esophageal Squamous Cell Carcinoma AJCC v8
- Pathologic Stage IA Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage IA Esophageal Squamous Cell Carcinoma AJCC v8
- Pathologic Stage IB Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage IB Esophageal Squamous Cell Carcinoma AJCC v8
- Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage II Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage II Esophageal Squamous Cell Carcinoma AJCC v8
- Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage IIA Esophageal Squamous Cell Carcinoma AJCC v8
- Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage IIB Esophageal Squamous Cell Carcinoma AJCC v8
- Pathologic Stage III Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage III Esophageal Squamous Cell Carcinoma AJCC v8
- Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage IIIA Esophageal Squamous Cell Carcinoma AJCC v8
- Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8
- Pathologic Stage IIIB Esophageal Squamous Cell Carcinoma AJCC v8
- Postneoadjuvant Therapy Stage I Esophageal Adenocarcinoma AJCC v8
- Postneoadjuvant Therapy Stage I Esophageal Squamous Cell Carcinoma AJCC v8
- Postneoadjuvant Therapy Stage II Esophageal Adenocarcinoma AJCC v8
- Postneoadjuvant Therapy Stage II Esophageal Squamous Cell Carcinoma AJCC v8
- Postneoadjuvant Therapy Stage III Esophageal Adenocarcinoma AJCC v8
- Postneoadjuvant Therapy Stage III Esophageal Squamous Cell Carcinoma AJCC v8
- Postneoadjuvant Therapy Stage IIIA Esophageal Adenocarcinoma AJCC v8
- Postneoadjuvant Therapy Stage IIIA Esophageal Squamous Cell Carcinoma AJCC v8
- Postneoadjuvant Therapy Stage IIIB Esophageal Adenocarcinoma AJCC v8
- Postneoadjuvant Therapy Stage IIIB Esophageal Squamous Cell Carcinoma AJCC v8
- Stage 0 Lung Cancer AJCC v8
- Stage I Lung Cancer AJCC v8
- Stage IA1 Lung Cancer AJCC v8
- Stage IA2 Lung Cancer AJCC v8
- Stage IA3 Lung Cancer AJCC v8
- Stage IB Lung Cancer AJCC v8
- Stage II Lung Cancer AJCC v8
- Stage IIA Lung Cancer AJCC v8
- Stage IIB Lung Cancer AJCC v8
- Stage III Lung Cancer AJCC v8
- Stage IIIA Lung Cancer AJCC v8
- Stage IIIB Lung Cancer AJCC v8
- Stage IIIC Lung Cancer AJCC v8

## Interventions

- **PROCEDURE:** Biospecimen Collection
- **DEVICE:** Cardiac Event Monitor
- **OTHER:** Chemoradiotherapy
- **RADIATION:** Radiation Therapy

## Key facts

- **NCT ID:** NCT04183218
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2019-09-23
- **Primary completion:** 2024-01-06
- **Final completion:** 2024-05-02
- **Target enrollment:** 24 (ACTUAL)
- **Last updated:** 2026-04-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04183218

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04183218, "Characterizing Chemo-Radiotherapy Treatment-Related Cardiac Changes". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT04183218. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*