Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

NCT04185883 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

610

Enrollment

INDUSTRY

Sponsor class

Conditions

Advanced Solid Tumors
Kirsten Rat Sarcoma (KRAS) pG12C Mutation

Interventions

DRUG: Sotorasib
DRUG: Trametinib
DRUG: RMC-4630
DRUG: Afatinib
DRUG: Pembrolizumab
DRUG: Panitumumab
DRUG: Carboplatin, pemetrexed, docetaxel, paclitaxel
DRUG: Atezolizumab
DRUG: Palbociclib
DRUG: MVASI® (bevacizumab-awwb)
DRUG: TNO155
DRUG: IV Chemotherapy (Regimen 1)
DRUG: IV Chemotherapy (Regimen 2)
DRUG: BI 1701963
DRUG: AMG 404
DRUG: Everolimus

Sponsor

Amgen