# Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)

> **NCT04187144** · PHASE3 · COMPLETED · sponsor: **GlaxoSmithKline** · enrollment: 1606 (actual)

## Conditions studied

- Urinary Tract Infections

## Interventions

- **DRUG:** Gepotidacin
- **DRUG:** Placebo matching nitrofurantoin
- **DRUG:** Nitrofurantoin
- **DRUG:** Placebo matching gepotidacin

## Key facts

- **NCT ID:** NCT04187144
- **Lead sponsor:** GlaxoSmithKline
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-04-23
- **Primary completion:** 2022-12-01
- **Final completion:** 2022-12-01
- **Target enrollment:** 1606 (ACTUAL)
- **Last updated:** 2023-07-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04187144

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04187144, "Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)". Retrieved via AI Analytics 2026-07-25 from https://api.ai-analytics.org/clinical/NCT04187144. Licensed CC0.

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