# Use of Fresh Platelet Rich Plasma With Concentrated Leukocytes or Fresh Platelet Rich Plasma Without Concentrated Leukocytes in the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial

> **NCT04187183** · NA · COMPLETED · sponsor: **Istituto Ortopedico Rizzoli** · enrollment: 132 (actual)

## Conditions studied

- Osteoarthritis, Knee

## Interventions

- **OTHER:** Fresh Platelet Rich Plasma with leukocyte
- **OTHER:** Fresh Platelet Rich Plasma without leukocyte

## Key facts

- **NCT ID:** NCT04187183
- **Lead sponsor:** Istituto Ortopedico Rizzoli
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-06-23
- **Primary completion:** 2024-10-03
- **Final completion:** 2024-10-03
- **Target enrollment:** 132 (ACTUAL)
- **Last updated:** 2025-01-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04187183

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04187183, "Use of Fresh Platelet Rich Plasma With Concentrated Leukocytes or Fresh Platelet Rich Plasma Without Concentrated Leukocytes in the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT04187183. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*