# The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract

> **NCT04189744** · PHASE3 · COMPLETED · sponsor: **London School of Hygiene and Tropical Medicine** · enrollment: 5436 (actual)

## Conditions studied

- Pregnancy Malaria
- Bacterial Vaginoses
- Trichomonas Vaginitis

## Interventions

- **DRUG:** IPTp-sulphadoxine-pyrimethamine plus metronidazole
- **DRUG:** IPTp-dihydroartemisinin-piperaquine plus metronidazole
- **DRUG:** IPTp-sulphadoxine-pyrimethamine

## Key facts

- **NCT ID:** NCT04189744
- **Lead sponsor:** London School of Hygiene and Tropical Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-12-15
- **Primary completion:** 2022-10-21
- **Final completion:** 2023-03-31
- **Target enrollment:** 5436 (ACTUAL)
- **Last updated:** 2023-05-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04189744

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04189744, "The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04189744. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*