# Estrogen and Fear in PTSD

> **NCT04192266** · PHASE3 · COMPLETED · sponsor: **The University of Texas Health Science Center, Houston** · enrollment: 83 (actual)

## Conditions studied

- PTSD

## Interventions

- **DRUG:** Estradiol
- **DRUG:** Placebo oral tablet
- **BEHAVIORAL:** Prolonged Exposure (PE) therapy

## Key facts

- **NCT ID:** NCT04192266
- **Lead sponsor:** The University of Texas Health Science Center, Houston
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-06-24
- **Primary completion:** 2024-05-29
- **Final completion:** 2024-12-02
- **Target enrollment:** 83 (ACTUAL)
- **Last updated:** 2026-01-09

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04192266

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04192266, "Estrogen and Fear in PTSD". Retrieved via AI Analytics 2026-07-12 from https://api.ai-analytics.org/clinical/NCT04192266. Licensed CC0.

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