# Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure

> **NCT04193553** · PHASE2 · COMPLETED · sponsor: **Centre Leon Berard** · enrollment: 77 (actual)

## Conditions studied

- Gastro Intestinal Stromal Tumour

## Interventions

- **DRUG:** Lenvatinib
- **DRUG:** Placebo
- **OTHER:** Best supportive care

## Key facts

- **NCT ID:** NCT04193553
- **Lead sponsor:** Centre Leon Berard
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-01-17
- **Primary completion:** 2024-01-30
- **Final completion:** 2024-04-26
- **Target enrollment:** 77 (ACTUAL)
- **Last updated:** 2024-06-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04193553

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04193553, "Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT04193553. Licensed CC0.

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