# Pain-related Fear as a Facilitator of Nocebo Hyperalgesia

> **NCT04197154** · NA · COMPLETED · sponsor: **Leiden University Medical Center** · enrollment: 72 (actual)

## Conditions studied

- Hyperalgesia
- Chronic Pain Syndrome
- Chronic Pain, Psychogenic
- Fear of Pain

## Interventions

- **BEHAVIORAL:** Threat manipulation (control, no threat)
- **BEHAVIORAL:** Threat manipulation
- **BEHAVIORAL:** Conditioning of moderate pain
- **BEHAVIORAL:** Conditioning of high pain
- **BEHAVIORAL:** Extinction

## Key facts

- **NCT ID:** NCT04197154
- **Lead sponsor:** Leiden University Medical Center
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2019-10-14
- **Primary completion:** 2020-02-14
- **Final completion:** 2020-02-14
- **Target enrollment:** 72 (ACTUAL)
- **Last updated:** 2020-02-19

## Collaborators

- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04197154

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04197154, "Pain-related Fear as a Facilitator of Nocebo Hyperalgesia". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04197154. Licensed CC0.

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