# WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

> **NCT04197934** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **Mayo Clinic** · enrollment: 56 (actual)

## Conditions studied

- Anaplastic Astrocytoma, IDH-Wildtype
- Glioblastoma, IDH-Wildtype
- Metastatic Lung Non-Small Cell Carcinoma
- Metastatic Malignant Neoplasm in the Central Nervous System
- Stage IV Lung Cancer AJCC v8

## Interventions

- **PROCEDURE:** Biospecimen Collection - blood samples
- **PROCEDURE:** Biospecimen Collection - CSF samples
- **PROCEDURE:** Computed Tomography
- **DRUG:** EGFR/EGFRvIII Inhibitor WSD0922-FU
- **PROCEDURE:** Magnetic Resonance Imaging
- **PROCEDURE:** Therapeutic Conventional Surgery

## Key facts

- **NCT ID:** NCT04197934
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2019-12-20
- **Primary completion:** 2022-10-30
- **Final completion:** 2031-02-06
- **Target enrollment:** 56 (ACTUAL)
- **Last updated:** 2026-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04197934

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04197934, "WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT04197934. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*