# Vitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (PUVENAFLD)

> **NCT04198805** · PHASE2 · COMPLETED · sponsor: **Naga P. Chalasani** · enrollment: 205 (actual)

## Conditions studied

- Non-Alcoholic Fatty Liver Disease
- Non-Alcoholic Fatty Liver
- Non-Alcoholic Steatohepatitis

## Interventions

- **DIETARY_SUPPLEMENT:** Vitamin E [(all-rac)-α-tocopheryl acetate]
- **DIETARY_SUPPLEMENT:** Omega-3 fatty acid (DHA EE)
- **COMBINATION_PRODUCT:** Omega-3 fatty acid (DHA EE) & Vitamin E [(all-rac)-α-tocopheryl acetate]
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT04198805
- **Lead sponsor:** Naga P. Chalasani
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-01-03
- **Primary completion:** 2022-09-01
- **Final completion:** 2022-09-01
- **Target enrollment:** 205 (ACTUAL)
- **Last updated:** 2023-05-25

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04198805

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04198805, "Vitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (PUVENAFLD)". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT04198805. Licensed CC0.

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