# Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants

> **NCT04209946** · NA · COMPLETED · sponsor: **Sharp HealthCare** · enrollment: 180 (actual)

## Conditions studied

- Premature Lungs
- Respiratory Distress Syndrome
- Surfactant Deficiency Syndrome Neonatal

## Interventions

- **PROCEDURE:** Less Invasive Surfactant Administration LISA
- **PROCEDURE:** Continuous Positive Airway Pressure CPAP

## Key facts

- **NCT ID:** NCT04209946
- **Lead sponsor:** Sharp HealthCare
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-01-22
- **Primary completion:** 2023-05-08
- **Final completion:** 2025-11-10
- **Target enrollment:** 180 (ACTUAL)
- **Last updated:** 2025-12-18

## Collaborators

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- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04209946

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04209946, "Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04209946. Licensed CC0.

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