# A 2-part Study to Investigate the Effect of Macitentan in Healthy Male Participants

> **NCT04211272** · PHASE1 · COMPLETED · sponsor: **Actelion** · enrollment: 47 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** Macitentan
- **DRUG:** Sildenafil
- **DRUG:** Riociguat
- **DRUG:** Rosuvastatin

## Key facts

- **NCT ID:** NCT04211272
- **Lead sponsor:** Actelion
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-01-14
- **Primary completion:** 2021-04-19
- **Final completion:** 2021-04-19
- **Target enrollment:** 47 (ACTUAL)
- **Last updated:** 2025-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04211272

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04211272, "A 2-part Study to Investigate the Effect of Macitentan in Healthy Male Participants". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT04211272. Licensed CC0.

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