# Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal

> **NCT04218240** · PHASE2 · COMPLETED · sponsor: **University of Pennsylvania** · enrollment: 90 (actual)

## Conditions studied

- Opioid Withdrawal

## Interventions

- **DRUG:** Pregabalin 200 MG capsules
- **DRUG:** Placebo oral tablet
- **DRUG:** Lofexidine 0.18Mg Tab

## Key facts

- **NCT ID:** NCT04218240
- **Lead sponsor:** University of Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-12-17
- **Primary completion:** 2023-08-31
- **Final completion:** 2023-08-31
- **Target enrollment:** 90 (ACTUAL)
- **Last updated:** 2024-09-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04218240

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04218240, "Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT04218240. Licensed CC0.

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