# Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

> **NCT04218617** · PHASE2 · RECRUITING · sponsor: **Case Comprehensive Cancer Center** · enrollment: 130 (estimated)

## Conditions studied

- Spine Metastases
- Spine Stereotactic Radiosurgery (sSRS)

## Interventions

- **DEVICE:** Diagnostic MRI
- **DEVICE:** Planning MRI
- **OTHER:** Simulation CT
- **OTHER:** QOL assessment
- **OTHER:** Brief pain inventory (BPI)
- **RADIATION:** sSRS in 1 fraction
- **RADIATION:** sSRS in 2 fraction

## Key facts

- **NCT ID:** NCT04218617
- **Lead sponsor:** Case Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2020-02-07
- **Primary completion:** 2026-10
- **Final completion:** 2026-10
- **Target enrollment:** 130 (ESTIMATED)
- **Last updated:** 2026-03-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04218617

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04218617, "Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT04218617. Licensed CC0.

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