# Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma

> **NCT04220749** · PHASE2 · RECRUITING · sponsor: **London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's** · enrollment: 68 (estimated)

## Conditions studied

- Head and Neck Cancer
- Oropharyngeal Squamous Cell Carcinoma

## Interventions

- **RADIATION:** Radiation
- **PROCEDURE:** Trans-Oral Surgery (TOS) + Neck Dissection

## Key facts

- **NCT ID:** NCT04220749
- **Lead sponsor:** London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2020-06-25
- **Primary completion:** 2028-02
- **Final completion:** 2028-02
- **Target enrollment:** 68 (ESTIMATED)
- **Last updated:** 2020-09-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04220749

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04220749, "Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma". Retrieved via AI Analytics 2026-06-14 from https://api.ai-analytics.org/clinical/NCT04220749. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*