# Stem Cell Transplantation in Crohn's Disease

> **NCT04224558** · PHASE1,PHASE2 · RECRUITING · sponsor: **Cedars-Sinai Medical Center** · enrollment: 15 (estimated)

## Conditions studied

- Crohn Disease

## Interventions

- **DRUG:** Mesna
- **DRUG:** Cyclophosphamide
- **DRUG:** Filgrastim
- **PROCEDURE:** Apheresis catheter placement
- **PROCEDURE:** Leukapheresis
- **DRUG:** Fludarabine
- **DRUG:** Methylprednisolone
- **DRUG:** Diphenhydramine
- **DRUG:** Acetaminophen
- **DRUG:** anti-thymocyte globulin (rabbit)
- **DRUG:** lymphocyte immune globulin
- **BIOLOGICAL:** Peripheral Blood Stem Cell Infusion
- **DRUG:** Cytoxan

## Key facts

- **NCT ID:** NCT04224558
- **Lead sponsor:** Cedars-Sinai Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2019-11-15
- **Primary completion:** 2027-09-30
- **Final completion:** 2027-09-30
- **Target enrollment:** 15 (ESTIMATED)
- **Last updated:** 2026-02-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04224558

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04224558, "Stem Cell Transplantation in Crohn's Disease". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT04224558. Licensed CC0.

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