# Amplatzer Amulet LAAO vs. NOAC

> **NCT04226547** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Abbott Medical Devices** · enrollment: 2650 (estimated)

## Conditions studied

- Atrial Fibrillation
- Stroke
- Bleeding

## Interventions

- **DEVICE:** Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder)
- **DRUG:** Non-Vitamin K Oral Antagonists

## Key facts

- **NCT ID:** NCT04226547
- **Lead sponsor:** Abbott Medical Devices
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2020-07-07
- **Primary completion:** 2029-01
- **Final completion:** 2031-04
- **Target enrollment:** 2650 (ESTIMATED)
- **Last updated:** 2026-02-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04226547

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04226547, "Amplatzer Amulet LAAO vs. NOAC". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT04226547. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*