# A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult Participants

> **NCT04235270** · PHASE1 · COMPLETED · sponsor: **Janssen Research & Development, LLC** · enrollment: 62 (actual)

## Conditions studied

- Healthy

## Interventions

- **COMBINATION_PRODUCT:** FDC of Macitentan and Tadalafil
- **DRUG:** Macitentan
- **DRUG:** Tadalafil

## Key facts

- **NCT ID:** NCT04235270
- **Lead sponsor:** Janssen Research & Development, LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2020-01-17
- **Primary completion:** 2020-07-17
- **Final completion:** 2020-07-17
- **Target enrollment:** 62 (ACTUAL)
- **Last updated:** 2025-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04235270

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04235270, "A Study of Macitentan and Tadalafil as a Fixed Dose Combination and the Free Combination in Healthy Adult Participants". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT04235270. Licensed CC0.

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