# Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery

> **NCT04244981** · PHASE4 · RECRUITING · sponsor: **SHI Jia** · enrollment: 820 (estimated)

## Conditions studied

- Cardiac Surgical Procedures

## Interventions

- **DRUG:** Prothrombin Complex Concentrate, Human
- **DRUG:** Fresh Frozen Plasma

## Key facts

- **NCT ID:** NCT04244981
- **Lead sponsor:** SHI Jia
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-10-25
- **Primary completion:** 2025-03-10
- **Final completion:** 2025-10-31
- **Target enrollment:** 820 (ESTIMATED)
- **Last updated:** 2025-10-27

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT04244981

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT04244981, "Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT04244981. Licensed CC0.

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